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On August 22, 2021 FDA issued a concurrence letter (PDF, 109 KB) , and on August 23, 2021, FDA revised the Fact Sheet for Healthcare Providers Administering Vaccine (Vaccination Providers) (1.3 MB) to provide updates on expiration dating of the authorized Pfizer-BioNTech COVID-19 Vaccine

doi:10.3390/ijms23052896 De Filippis F, Pasolli E, Ercolini D

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[76] The first published report of successful treatment with vitamin K of life-threatening hemorrhage in a jaundiced patient with prothrombin deficiency was made in 1938 by Smith, Warner, and Brinkhous